反应 #2006432

反应方程式

4-nitro-2,2′-bipyridyl-N-oxide

acetyl bromide

→

4-bromo-2,2′-bipyridyl-N-oxide

收率 95.0%

溶剂

acetic acid

反应条件

后处理

1. 1
   温度The yellow mixture was refluxed for 1.5 h
2. 2
   其他The resulting light yellow solid was sufficiently pure enough for the next step without further purification

实验过程

To 4-nitro-2,2′-bipyridyl-N-oxide (Wenkert, D.; Woodward, R. B. J. Org. chem. 48,283 (1983)) (5 g) dissolved in 30 mL acetic acid in a 100 ml round bottom flask was added 16 mL acetyl bromide. The yellow mixture was refluxed for 1.5 h and then rotovaporated to dryness. The resulting light yellow solid was sufficiently pure enough for the next step without further purification. Yield: 95%

来源