反应 #1985944

ord-cf38f96581534566aa8c89c9a242ad2a

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    洗涤the organic layer washed with water, brine
  2. 2
    干燥dried over magnesium sulfate
  3. 3
    过滤filtered
  4. 4
    浓缩concentrated in vacuo

实验过程

To a solution of methyl 5-acetoxy-2-formyl-4-methoxyhydrocinnamate (3.31 g) and imidazole (2.42 g) in methylene chloride (25 ml) is added a solution of tert-butylchlorodimethylsilane (2.73 g) in methylene chloride (25 ml). The mixture is stirred at room temperature for about 60 minutes, diluted with ether and water, and the organic layer washed with water, brine, dried over magnesium sulfate, filtered and concentrated in vacuo to give the desired product.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US05571506uspto-grants-1996_11