反应 #1973965

反应方程式

4-chloro-3-nitroaniline

methanesulfonyl chloride

pyridine

→

title compound

收率 92.2%

N-(4-chloro-3-nitrophenyl)methanesulfonamide

收率 92.2%

溶剂

THF

HCl

反应条件

后处理

1. 1
   过滤The resulting precipitate was filtered
2. 2
   其他air-dried

实验过程

A mixture of 4-chloro-3-nitroaniline (5.0 g, 29 mmol), methanesulfonyl chloride (2.37 mL, 30.4 mmol) and pyridine (5.9 mL, 72.4 mmol) in THF (100 mL) was stirred for 24 h. Poured in 1M HCl (500 mL). The resulting precipitate was filtered and air-dried to provide the title compound as a solid (6.7 g, 92%).

来源