反应 #1973928

ord-2c5e79c602a84d9fa0caec80d5c30337

反应方程式

CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
5c
CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
2-(12-phthalimido dodecyl)propane dioic acid di-tert-butyl ester
O=C(O)C(F)(F)F
trifluoroacetic acid
→
O=C(O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)O
2-(12-phthalimido dodecyl)propane dioic acid
收率 100.0%

反应物

CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
5c
CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
2-(12-phthalimido dodecyl)propane dioic acid di-tert-butyl ester
O=C(O)C(F)(F)F
trifluoroacetic acid

试剂

无

溶剂

ClCCl
dichloromethane

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

Following general procedure D, 16.0 mmol (8.45 g) of 5c and 160 mmol (11.9 mL) of trifluoroacetic acid were reacted in 12 mL of dichloromethane at room temperature and the mixture was processed. Yield 100%.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US08501199B2uspto-grants-2013_08