反应 #1973926

反应方程式

diisopropyl azo dicarboxylate

20-Bromoeicosan-1-ol

triphenylphosphine

phthalimide

→

N-(20-Bromoeicosyl)phthalimide

收率 66.0%

溶剂

tetrahydrofuran

反应条件

后处理

1. 1
   其他The crude product was purified by column chromatography (toluene)

实验过程

Following general procedure A, 69.4 mmol (26.2 g) of 20-Bromoeicosan-1-ol, 76.3 mmol (20.0 g) of triphenylphosphine, 76.3 mmol (11.2 g) of phthalimide and 76.3 mmol (15.5 mL) of diisopropyl azo dicarboxylate were reacted in 300 mL of tetrahydrofuran for 1 d and the mixture was processed accordingly. The crude product was purified by column chromatography (toluene). Yield 66%.

来源