反应 #1914865

反应方程式

4-8

3-(5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl)-acrylic acid ethyl ester

hydrogen

→

4-9

3-(5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl)-propionic acid ethyl ester

溶剂

EtOH

反应条件

后处理

1. 1
   过滤Filtration
2. 2
   其他removal of the solvent

实验过程

A mixture of 4-8 (1.4 g, 6.03 mmol) and 10% Pd/carbon (1 g) in EtOH (30 mL) was stirred under a balloon of hydrogen for 18 h. Filtration and evaporative removal of the solvent gave 4-9 as a white solid.

来源