反应 #1914821

反应方程式

dichloro(β-cyano)ethoxyphosphine

diisopropylethylamine

diisopropylamine

→

Diisopropylaminochloro(β-cyano)ethoxyphosphine

溶剂

dichloromethane

反应条件

后处理

1. 1
   其他the reaction mixture is ready for the next step reaction

实验过程

To a solution of 0.54 mL(4.0 mmol) of dichloro(β-cyano)ethoxyphosphine in 40 mL of dichloromethane cooled in an ice-water bath was added 10 mL of diisopropylethylamine, followed by adding 0.64 mL (4.0 mmol) of diisopropylamine under Argon. The reaction mixture was warmed up to room temperature and stirred for 2 h. After adding 0.1 gm of DMAP into the solution, the reaction mixture is ready for the next step reaction.

来源