反应 #1885089

反应方程式

4a

2-Phenyl-2,5-dihydro-pyrazolo-(4,3-c) quinolin-3-one

3h

Ethyl 4-chloro-6-trifluoromethyl-quinoline-3-carboxylate

phenyl hydrazine

→

title compound

2-Phenyl-8-trifluoromethyl-2,5-dihydro-pyrazolo-(4,3-c)quinolin-3-one

反应条件

实验过程

The title compound was prepared following the procedure described in Step 3 of the synthesis of 4a, using 3h and phenyl hydrazine. 1H NMR (DMSO-d6) δ (ppm):7.21 (1H, m), 7.42 (2H, t, J=7.56 Hz), 7.97 (1H, d, J=2.20 Hz), 8.00 (1H, d, J=2.20 Hz), 8.20 (1H, ddd, J=7.41, 1.10, 0.83 Hz), 8.43 (2H, dd, J=1.33, 0.83 Hz), 8.82 (1H, s). m/z 330.2 (MH+).

来源