反应 #1885078

反应方程式

3a

Ethyl 4-chloro-quinoline-3-carboxylate

2b

Ethyl 6-fluoro-4-hydroxy-quinoline-3-carboxylate

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title compound

Ethyl 4-chloro-6-fluoro-quinoline-3-carboxylate

反应条件

实验过程

The title compound was prepared following the procedure described in Step 2 for the synthesis of 3a using 2b instead of 2a. 1H NMR (CDCl3) δ (ppm): 1.47 (3H, t, J=7.08 Hz), 4.51 (2H, q, J=7.08 Hz), 7.63 (1H, m), 8.02 (1H, dd, J=9.52, 2.68 Hz), 8.15 (1H, dd, J=9.27, 5.37 Hz), 9.15 (1H, s). m/z 254.6 (MH+).

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