反应 #1885073

反应方程式

ethyl 4-chloro-quinoline-3-carboxylate

Ethyl 4-chloro-quinoline-3-carboxylate

triethylamine

phenyl hydrazine

→

crude product

2-Phenyl-2,5-dihydro-pyrazolo-(4,3-c) quinolin-3-one

溶剂

o-xylene

反应条件

实验过程

A suspension of ethyl 4-chloro-quinoline-3-carboxylate (3a) (2.35 g, 0.01 M) in 20 mL of o-xylene was refluxed with triethylamine (2.0 mL, 0.02 M) and phenyl hydrazine (2.89 g, 0.02 M) overnight. The crude product was obtained by filtration followed by washing the solid with cold methanol.

来源