反应 #1869202
ord-60614bbfc0554c2f9387e571239d1365
反应方程式
1,1-dimethylethyl {1-[2-(4-quinolinyl)ethyl]-4-piperidinyl}carbamate
chloroform
→
product
收率 100.0%
1-[2-(4-quinolinyl)ethyl]-4-piperidinamine trihydrochloride
收率 100.0%
反应条件
详细条件
See reaction.notes.procedure_details.
后处理
- 1其他the reaction mixture was evaporated to dryness
实验过程
1,1-dimethylethyl {1-[2-(4-quinolinyl)ethyl]-4-piperidinyl}carbamate (9a) (278 mg) was dissolved in chloroform and diluted with 4N HCl in dioxane solution. After stirring two hours, the reaction mixture was evaporated to dryness to afford the product as a solid (180 mg, 100%).