反应 #1824357

反应方程式

2-benzylidenecyclohexanone

→

cis-2-benzylcyclohexanol

trans-2-benzylcyclohexanol

收率 88.0%

溶剂

methanol

反应条件

后处理

1. 1
   其他were hydrogenated at room temperature
2. 2
   其他until the absorption of hydrogen
3. 3
   其他After an organic layer was collected by decantation
4. 4
   浓缩concentrated
5. 5
   其他the residue was purified by column chromatography

实验过程

Then, 10 g of 2-benzylidenecyclohexanone were hydrogenated at room temperature using 1 g of Raney nickel in methanol under hydrogen pressure (3 kg/cm2) until the absorption of hydrogen was stopped. After an organic layer was collected by decantation and concentrated, the residue was purified by column chromatography, thereby obtaining 4.6 g of cis-2-benzylcyclohexanol and 4.4 g of trans-2-benzylcyclohexanol (yield: 88% in total).

来源