反应 #1824353

反应方程式

4-benzyl-2-cyclohexen-1-one

→

cis-4-benzylcyclo-hexanol

trans-4-benzylcyclohexanol

收率 90.0%

溶剂

methanol

反应条件

后处理

1. 1
   其他until the absorption of hydrogen
2. 2
   其他After an organic layer was collected by decantation
3. 3
   浓缩concentrated
4. 4
   其他the residue was purified by column chromatography

实验过程

Besides, 30 g of the above-obtained 4-benzyl-2-cyclohexen-1-one were hydrogenated at room temperature for 6 hours using 5 g of Raney nickel in methanol under hydrogen pressure (3 kg/cm2) until the absorption of hydrogen was stopped. After an organic layer was collected by decantation and concentrated, the residue was purified by column chromatography, thereby obtaining 13 g of cis-4-benzylcyclo-hexanol and 14 g of trans-4-benzylcyclohexanol (yield: 90% in total).

来源