反应 #1824332

反应方程式

Lawsone

3,3-dimethylbutyric acid

ammonium peroxysulphate

→

title compound

2-(2.2-dimethylpropyl)-3-hydroxy-naphthalene-1 4-dione

溶剂

acetonitrile

water

water

反应条件

后处理

1. 1
   其他This compound was prepared by the general methods
2. 2
   温度the mixture heated for 1 hour

实验过程

This compound was prepared by the general methods as described in Examples 1 to 15. Lawsone (0.15 g), 3,3-dimethylbutyric acid (0.15 g), and silver nitrate (0.15 g) were heated in a mixture of acetonitrile (5 ml) and water (5 ml) at 60-65° C. A solution of ammonium peroxysulphate (0.3 g) in water (5 ml) was added dropwise and the mixture heated for 1 hour and then processed as for Example 3 to yield the title compound . The crude product was purified on a silica gel column using 20% diethyl ether in petroleum ether eluant and recrystallised from petroleum ether to yield 38 mg of the title compound.

来源