反应 #1824322

反应方程式

1-(2-ethylhexyl)-2-trichloromethylbenzimidazole

o-aminophenol

triethylamine

→

2-(1-(2-Ethylhexyl)-benzimidazol-2-yl)-benzoxazole

溶剂

ethanol

反应条件

后处理

1. 1
   其他The ethanol is subsequently removed on a rotary evaporator, ethyl acetate
2. 2
   workup.ADDITIONis added to the residue which
3. 3
   洗涤the mixture is washed with water
4. 4
   干燥dried over sodium sulfate

实验过程

28.2 g (0.12 mol) of 1-(2-ethylhexyl)-2-trichloromethylbenzimidazole (prepared by reacting N-2-ethylhexyl-o-phenylenediamine with trichloroacetamido methyl ester), 13.1 g (0.12 mot) of o-aminophenol and 39.4 g (0.38 mot) of triethylamine in 150 ml of ethanol are stirred at room temperature for 15 hours. The ethanol is subsequently removed on a rotary evaporator, ethyl acetate is added to the residue which remains, and the mixture is washed with water and dried over sodium sulfate. 35% of product is identified by BPLC in the product mixture thus ob-5 tained; isolation can be carried out, for example, by column chromatography.

来源