反应 #1820428

ord-d3779bacaf7f45dba5bbbdaefa62f7f5

反应方程式

O=C[C@H](O)[C@@H](O)[C@@H](O)CO
L-arabinose
C=CCN
2-propenylamine
O=C=NCCCl
2-chloroethyl isocyanate
C=CCN(C(=O)NCCCl)C1OC[C@H](O)[C@H](O)[C@H]1O
1-(2-chloroethyl)-3-(2-propenyl)-3-(L-arabinopyranosyl)urea
收率 62.3%

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

4.5 g of L-arabinose, 2.5 g of 2-propenylamine and 3.5 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 31-(1). 5.5 g of 1-(2-chloroethyl)-3-(2-propenyl)-3-(L-arabinopyranosyl)urea are thereby obtained as colorless powder.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US04241052uspto-grants-1980_12