反应 #1820422

ord-eabc4d3d17194d93aaeb2d372e53db19

反应方程式

O=C[C@H](O)[C@@H](O)[C@@H](O)CO
L-arabinose
NCC1CC1
cyclopropylmethylamine
O=C=NCCCl
2-chloroethyl isocyanate
O=C(NCCCl)N(CC1CC1)C1OC[C@H](O)[C@H](O)[C@H]1O
1-(2-chloroethyl)-3-cyclopropylmethyl-3-(L-arabinopyranosyl) urea
收率 38.9%

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

3.0 g of L-arabinose, 2.2 g of cyclopropylmethylamine and 2.5 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 23-(1). 2.4 g of 1-(2-chloroethyl)-3-cyclopropylmethyl-3-(L-arabinopyranosyl) urea are thereby obtained as colorless caramel.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US04241052uspto-grants-1980_12