反应 #1811

反应方程式

ammonia

isothiocyanatoacetaldehyde dimethyl acetal

→

title compound

N-(2,2-Dimethoxyethyl)thiourea

溶剂

Methanol

反应条件

后处理

1. 1
   浓缩The mixture was concentrated
2. 2
   其他the residue was chromatographed (silica gel, 5% methanol/dichloromethane)

实验过程

Methanol (200 mL) was saturated with ammonia and stirred with isothiocyanatoacetaldehyde dimethyl acetal (5.0 g) for 2 h. The mixture was concentrated and the residue was chromatographed (silica gel, 5% methanol/dichloromethane) to give the title compound.

来源