反应 #1810835

反应方程式

4-amino-3-mercapto-6-methyl-4H-1,2,4-triazin-5-one

benzyl chloride

sodium hydroxide

→

4-amino-3-benzylsulfanyl-6-methyl-4H-1,2,4-triazin-5-one

溶剂

ethanol

water

反应条件

后处理

1. 1
   过滤The resultant precipitate was filtered off with suction

实验过程

0.272 g of 4-amino-3-mercapto-6-methyl-4H-1,2,4-triazin-5-one (which can be prepared by the method of A. Dornow, H. Menzel, P. Marx, Chem. Ber. 97, 2173 (1964)) was suspended in 0.86 ml of a 2N solution of sodium hydroxide in water. A solution of 0.218 g of benzyl chloride in ethanol was subsequently added dropwise, and the mixture was heated at 80° C. for 30 minutes. The resultant precipitate was filtered off with suction, giving 4-amino-3-benzylsulfanyl-6-methyl-4H-1,2,4-triazin-5-one.

来源