反应 #1810833

ord-19904cf2407c4ab583ea37516f0e08d1

反应方程式

CC(C)Oc1ccc(C#N)cc1C(=O)O
5-cyano-2-isopropoxy-benzoic acid
Cl.Clc1ccc(C2=CCNCC2)cc1
4-(4-chloro-phenyl)-1,2,3,6-tetrahydro-pyridine hydrochloride
CC(C)Oc1ccc(C#N)cc1C(=O)N1CC=C(c2ccc(Cl)cc2)CC1
title compound
CC(C)Oc1ccc(C#N)cc1C(=O)N1CC=C(c2ccc(Cl)cc2)CC1
3-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridine-1-carbonyl]-4-isopropoxy-benzonitrile

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他described for the synthesis of example 4, step f

实验过程

According to the procedure described for the synthesis of example 4, step f, the title compound has been synthesized from 5-cyano-2-isopropoxy-benzoic acid (CAS: 845616-14-0) and 4-(4-chloro-phenyl)-1,2,3,6-tetrahydro-pyridine hydrochloride (commercial). MS (m/e): 381.1 (MH+, 100%).

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07485637B2uspto-grants-2009_02