反应 #1810832

ord-269b625e994b426db22386ba5f18cfb7

反应方程式

CS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)O)c1
2-cyclopentyloxy-5-methanesulfonyl-benzoic acid
CS(=O)(=O)c1ccc(C2=CCNCC2)cc1
4-(4-Methanesulfonyl-phenyl)-1,2,3,6-tetrahydro-pyridine
→
CS(=O)(=O)c1ccc(C2=CCN(C(=O)c3cc(S(C)(=O)=O)ccc3OC3CCCC3)CC2)cc1
title compound
CS(=O)(=O)c1ccc(C2=CCN(C(=O)c3cc(S(C)(=O)=O)ccc3OC3CCCC3)CC2)cc1
(2-Cyclopentyloxy-5-methanesulfonyl-phenyl)-[4-(4-methanesulfonyl-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-methanone

反应物

CS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)O)c1
2-cyclopentyloxy-5-methanesulfonyl-benzoic acid
CS(=O)(=O)c1ccc(C2=CCNCC2)cc1
4-(4-Methanesulfonyl-phenyl)-1,2,3,6-tetrahydro-pyridine

试剂

无

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他described for the synthesis of example 4, step f

实验过程

According to the procedure described for the synthesis of example 4, step f, the title compound has been synthesized from 2-cyclopentyloxy-5-methanesulfonyl-benzoic acid and 4-(4-Methanesulfonyl-phenyl)-1,2,3,6-tetrahydro-pyridine. MS (m/e): 503.9 (M+, 100%)

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07485637B2uspto-grants-2009_02