反应 #1810818

ord-dd02f8d55c4346c2bc68904933abdfa5

反应方程式

O=C(Cl)c1cc([N+](=O)[O-])ccc1N1CCOCC1
2-morpholin-4-yl-5-nitro-benzoyl chloride
Cl.Clc1ccc(C2=CCNCC2)cc1
4-(4-Chloro-phenyl)-1,2,3,6-tetrahydro-pyridine hydrochloride
O=C(c1cc([N+](=O)[O-])ccc1N1CCOCC1)N1CC=C(c2ccc(Cl)cc2)CC1
title compound
O=C(c1cc([N+](=O)[O-])ccc1N1CCOCC1)N1CC=C(c2ccc(Cl)cc2)CC1
[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-(2-morpholin-4-yl-5-nitrophenyl) methanone

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他described for the synthesis of example 1

实验过程

According to the procedure described for the synthesis of example 1, the title compound has been synthesized from 2-morpholin-4-yl-5-nitro-benzoyl chloride and 4-(4-Chloro-phenyl)-1,2,3,6-tetrahydro-pyridine hydrochloride (commercial). MS (m/e): 428.1 (MH+, 100%)

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07485637B2uspto-grants-2009_02