反应 #1810810

反应方程式

1-(trans-4-aminocyclohexyl)-1-methyl-thiourea

hydrochloride

methyliodide

→

hydrochloride

hydroiodide

1-(trans-4-aminocyclohexyl)-1,2-dimethyl-isothiourea

溶剂

MeOH

反应条件

后处理

1. 1
   温度is refluxed for 2 hours
2. 2
   其他solvent is evaporated

实验过程

A mixture of 0.6 g of 1-(trans-4-aminocyclohexyl)-1-methyl-thiourea in the form of a hydrochloride in 30 ml of MeOH and 0.22 ml of methyliodide is refluxed for 2 hours, solvent is evaporated and 1-(trans-4-aminocyclohexyl)-1,2-dimethyl-isothiourea in the form of a hydrochloride and a hydroiodide is obtained.

来源