反应 #1797546

ord-03c4529878534be09bceed2bfcc11944

反应方程式

O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
Intermediate 3
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
CNCCO
2-(methylamino)ethanol
CN(CCO)c1c(C(=O)NC2C3CC4CC(C3)CC2C4)cnn1-c1ccccc1
5-[(2-Hydroxy-ethyl)-methyl-amino]-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

5-[(2-Hydroxy-ethyl)-methyl-amino]-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide was prepared using Procedure A from 5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide (Intermediate 3) and 2-(methylamino)ethanol. Mass spectrum (ES) MH+=396.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07790711B2uspto-grants-2010_09