反应 #1797533

ord-d4ad9563d3004515ae82680136e8a20b

反应方程式

O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
Intermediate 3
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
CC1CNCC(C)O1
2,6-dimethylmorpholine
CC1CN(c2c(C(=O)NC3C4CC5CC(C4)CC3C5)cnn2-c2ccccc2)CC(C)O1
5-(2,6-Dimethyl-morpholin-4-y1)-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

5-(2,6-Dimethyl-morpholin-4-y1)-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide was prepared using Procedure A from 5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide (Intermediate 3) and 2,6-dimethylmorpholine. Mass spectrum (ES) MH+=435.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07790711B2uspto-grants-2010_09