反应 #1797510

ord-a170e721fba843efacca68a3b168ba58

反应方程式

COc1ccc(Cl)cc1B(O)O
2-methoxy-5-chlorophenylboronic acid
O=C(O)c1ccc(B(O)O)cc1
4-carboxyphenylboronic acid
O=C(O)c1cncc(Br)c1
5-bromonicotinic acid
COc1ccc(Cl)cc1-c1cncc(C(=O)O)c1
title compound
COc1ccc(Cl)cc1-c1cncc(C(=O)O)c1
5-(5-chloro-2-methoxyphenyl)-nicotinic Acid

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

Following the procedure of Example 1b), except substituting 2-methoxy-5-chlorophenylboronic acid; for 4-carboxyphenylboronic acid; and substituting 5-bromonicotinic acid; for the compound of 1a), the title compound was prepared. MS (ES) m/z 264 [M+H].

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07790704B2uspto-grants-2010_09