反应 #1787637

反应方程式

5-(2-chlorophenyl)-2-propionylcyclohexane-1,3-dione

hydrazine hydrate hydrazine hydrate

→

6-(2-chlorophenyl)-3-ethyl-4,5,6,7-tetrahydroindazol-4-one

收率 142.7%

溶剂

ethanol

反应条件

后处理

1. 1
   其他Under reduced pressure, the solvent was evaporated
2. 2
   其他the residue was recrystallized from ethyl acetate-hexane

实验过程

A solution of 5-(2-chlorophenyl)-2-propionylcyclohexane-1,3-dione (0.6 g) and hydrazine hydrate hydrazine hydrate (0.12 g) in ethanol (20 ml) was refluxed for 2 hours. Under reduced pressure, the solvent was evaporated, and the residue was recrystallized from ethyl acetate-hexane to give colorless crystals of 6-(2-chlorophenyl)-3-ethyl-4,5,6,7-tetrahydroindazol-4-one (0.47 g).

来源