反应 #1771990

ord-56238b79bf8e4876a8c816dff94dc2f6

反应方程式

CC1(C)CN(C(=O)OC(C)(C)C)[C@@](C(=O)O)(C(C)(C)C)C1
tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline
CC1(C)CN[C@H](C(=O)O)C1
4,4-Dimethylproline

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    浓缩The solution was concentrated
  2. 2
    其他dried under high vacuum
  3. 3
    其他taken to the next step without further purification

实验过程

A solution of tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline in dichloromethane (5 mL) and trifluoroacetic (5 mL) was stirred at room temperature for five hours. The solution was concentrated, dried under high vacuum and taken to the next step without further purification.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: USRE043298E1uspto-grants-2012_04