反应 #1747868

反应方程式

triethylamine

benzoyl chloride

10-(4-hydroxyphenyl)phenothiazine 5,5-dioxide

→

4-(5,5-Dioxophenothiazin-10-yl)phenyl benzoate

溶剂

acetonitrile

反应条件

后处理

1. 1
   workup.DISTILLATIONthe solvent was distilled off
2. 2
   workup.STIRRINGstirred at 75° C. for 30 min
3. 3
   过滤The solid was filtered off with suction while hot,
4. 4
   洗涤washed with hot water
5. 5
   其他dried at 120° C. in a forced-air drying cabinet
6. 6
   其他were obtained

实验过程

0.68 g (6.68 mmol) of triethylamine and 0.34 g (2.44 mmol) of benzoyl chloride were added to a solution of 0.72 g (2.22 mmol) of 10-(4-hydroxyphenyl)phenothiazine 5,5-dioxide in 120 ml of acetonitrile. After stirring at room temperature for 45 min, the solvent was distilled off. The residue was taken up in 100 ml of hot water and stirred at 75° C. for 30 min. The solid was filtered off with suction while hot, washed with hot water and dried at 120° C. in a forced-air drying cabinet. 0.87 g (92% of theory) of colorless microcrystals having an m.p. of 233-235° C. were obtained.

来源