反应 #1702142

反应方程式

3-(3-nitrophenyl)propan-1-ol

→

desired product

收率 96.0%

3-(3-Aminophenyl)propan-1-ol

收率 96.0%

溶剂

methanol

反应条件

后处理

1. 1
   其他was hydrogenated at 50 psi overnight
2. 2
   过滤The reaction mixture was then filtered
3. 3
   浓缩concentrated

实验过程

To a solution of 3-(3-nitrophenyl)propan-1-ol (2.70 g, 14.9 mmol) in methanol (50.0 mL) was added 10% palladium on carbon (0.54 g, 0.46 mmol). The resultant mixture was hydrogenated at 50 psi overnight. The reaction mixture was then filtered and concentrated to give the desired product as a light brown thick oil (2.16 g, 96%). LCMS for C9H14NO (M+H)+: m/z=152.1.

来源