反应 #1702112

反应方程式

2-(3-nitrophenyl)ethanol

→

desired product

收率 99.0%

2-(3-Aminophenyl)ethanol

收率 99.0%

溶剂

methanol

反应条件

后处理

1. 1
   其他was hydrogenated at 45 psi overnight
2. 2
   过滤The resultant mixture was filtered
3. 3
   浓缩concentrated

实验过程

Into a pressure bottle were added 2-(3-nitrophenyl)ethanol (3.0 g, 18 mmol) and methanol (100 mL) and 10% palladium on carbon (0.1 g, 0.08 mmol). The reaction mixture was hydrogenated at 45 psi overnight. The resultant mixture was filtered and concentrated to provide the desired product (2.44 g, 99%) as a white solid. LCMS for C8H12NO (M+H)+: m/z=138.1.

来源