反应 #170166

反应方程式

Thionyl chloride

3-(2-thienyl)propanol

→

title compound

2-(3-Chloropropyl)thiophene

溶剂

THF

反应条件

后处理

1. 1
   浓缩concentrated to dryness

实验过程

Thionyl chloride (420 μL, 5.7 mmol) was added to a solution of 3-(2-thienyl)propanol (682.0 mg, 4.8 mmol) in THF (3 mL) at room temperature. The reaction mixture was stirred at 50° C. for 2 hours and then concentrated to dryness to afford the title compound as a brown oil. The product was used in the next step without further purification.

来源