反应 #1687619

反应方程式

3-Cyanopyridine

methyl iodide

methyl iodide

→

title compound

收率 81.0%

3-Cyano-1-methylpyridinium Iodide

收率 81.0%

溶剂

acetone

反应条件

后处理

1. 1
   过滤The mixture was filtered
2. 2
   洗涤the solid product was washed with acetone (100 ml)
3. 3
   其他After drying

实验过程

3-Cyanopyridine (1) (104 g, 1 mol) and methyl iodide (150 g, 1.06 mol) in acetone (500 ml) was stirred for 5 hours at room temperature. Then more methyl iodide (20 g, 0.14 mol) was added, and the reaction mixture was stirred overnight at room temperature. The mixture was filtered and the solid product was washed with acetone (100 ml) and then thoroughly with ether. After drying, 199 g (0.81 mol, 81%) of the title compound were obtained, M.P. 145°-150° C.

来源