反应 #163528

反应方程式

2,4-Dimethoxybenzoyl chloride

NaH

oxazinone

THF

→

4-(2,4-dimethoxyphenylcarbonyl)-2-ethyl-8-(prop-1-enyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

收率 84.0%

反应条件

后处理

1. 1
   其他109 mg of P9 were obtained

实验过程

Procedure & NMR Data: 162 mg (2.5 eq, 0.8 mmol) of 2,4-Dimethoxybenzoyl chloride was added to a mixture of 49 mg (4 eq, 1.28 mmol) of NaH and 73 mg (0.32 mmol) of oxazinone P2 in THF (14 mL). 109 mg of P9 were obtained, yield 84%.

来源