反应 #163345

反应方程式

N-[2-(4-iodo-phenyl)-1-methyl-ethyl]-acetamide

→

2-(4-Iodo-phenyl)-1-methyl-ethylamine

溶剂

HCl

反应条件

后处理

1. 1
   温度at reflux over night
2. 2
   workup.ADDITIONThen the mixture is diluted with soda lye
3. 3
   萃取extracted with EtOAc
4. 4
   干燥The organic layer is dried with Na2SO4
5. 5
   其他the solvent is removed in vacuo

实验过程

9.00 g (29.69 mmol) N-[2-(4-iodo-phenyl)-1-methyl-ethyl]-acetamide (I52.1) are added to 150 mL HCl (4N) and the reaction mixture is stirred at reflux over night. Then the mixture is diluted with soda lye and extracted with EtOAc. The organic layer is dried with Na2SO4 and the solvent is removed in vacuo.

来源