反应 #160606

反应方程式

5,6-difluoro-N1-(4-fluoro-2-iodophenyl)-3-methoxybenzene-1,2-diamine

1,1′-Carbonyldiimidazole

→

6,7-Difluoro-1-(4-fluoro-2-iodophenyl)-4-methoxy-1H-benzo[d]imidazol-2(3H)-one

溶剂

CH2Cl2

反应条件

后处理

1. 1
   其他precipitated out
2. 2
   过滤The white solid was filtered
3. 3
   其他used further without any purification

实验过程

To the stirred solution of 5,6-difluoro-N1-(4-fluoro-2-iodophenyl)-3-methoxybenzene-1,2-diamine (0.17 gm, 0.43 mmol) in CH2Cl2 (2 ml), 1,1′-Carbonyldiimidazole (0.085 gm, 0.53 mmol) was added. This reaction mixture was kept stirring at room temperature for 16 hours when product precipitated out. The white solid was filtered and used further without any purification. (0.089 gm); m/z=419 [M−1]−.

来源