反应 #1605762

ord-8817ac4656f64b428d6c6bc998600c13

反应方程式

Cc1ccc(C(=O)O)cc1C
3,4-dimethylbenzoic acid
CC(C)C[C@H](CO)NN
(R)-aminoleucinol
Cc1ccc(C(=O)N[C@@H](CO)CC(C)C)cc1C
(R)—N-(1-hydroxy-4-methylpentan-2-yl)-3,4-dimethylbenzamide
收率 75.0%

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

(R)—N-(1-hydroxy-4-methylpentan-2-yl)-3,4-dimethylbenzamide was prepared in a similar manner as described in example 4 using 3,4-dimethylbenzoic acid and with (R)-aminoleucinol. Yield: 75%. MS (M+H, 250.3).

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US09072313B2uspto-grants-2015_07