反应 #1597033

反应方程式

Cyclohexylmethyl bromide

sodium azide

DMSO

→

title compound

Cyclohexylmethyl Azide

反应条件

后处理

1. 1
   其他the reaction was quenched by the addition of water (5 mL)
2. 2
   萃取extracted with diethyl ether (3×4 mL)
3. 3
   洗涤The combined organic layers were washed with brine (5 mL)
4. 4
   干燥dried (MgSO4)
5. 5
   过滤filtered
6. 6
   浓缩concentrated in vacuo

实验过程

Cyclohexylmethyl bromide (200 mg, 1.13 mmol) was added to a stirred solution of 0.5 M sodium azide in DMSO (2.48 mL, 1.24 mmol) at room temperature, under an atmosphere of nitrogen. After 21 h, the reaction was quenched by the addition of water (5 mL) and extracted with diethyl ether (3×4 mL). The combined organic layers were washed with brine (5 mL), dried (MgSO4), filtered and concentrated in vacuo to afford the title compound as a crude oil (136 mg) which was used without further purification.

来源