反应 #1597020

ord-b4584d49a54b4f1e87fd4be68b04716d

反应方程式

O=C(O)c1cc(Cl)ccc1O
5-chlorosalicylic acid
N#Cc1cccc(N)c1
3-aminobenzonitrile
N#Cc1cccc(NC(=O)c2cc(Cl)ccc2O)c1
5-Chloro-N-(3-cyanophenyl)-2-hydroxybenzamide

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他This material was prepared

实验过程

This material was prepared according to the method of Example 1 using 5-chlorosalicylic acid and 3-aminobenzonitrile, with reagents and solvents employed in similar molar ratios. 1HNMR (500 MHz, DMSO-d6): δ 3.72 (s, 3H), 6.74 (m, 1H), 7.05 (m, 1H), 7.45 (m, 1H), 7.58 (br m, 2H), 7.83 (m, 1H), 7.88 (m, 1H), 8.19 (br s, 1H), 10.59 (s, 1H).

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US08211882B2uspto-grants-2012_07