反应 #1597005

反应方程式

5-aminosalicylic acid

4-chlorobenzyl chloride

→

5-(4-chlorobenzyl)aminosalicylic acid

收率 53.0%

反应条件

后处理

1. 1
   其他in Synthesis Example 1

实验过程

By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-chlorobenzyl chloride (630 mg, 3.91 mmole), 480 mg (53% yield) of 5-(4-chlorobenzyl)aminosalicylic acid was obtained as a white solid.: mp 227-228° C.

来源