反应 #159175

反应方程式

1-(3a,6a-Dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone

phenyltrimethylammonium tribromide

→

title compound

2-Bromo-1-(3a,6a-dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone

溶剂

THF

反应条件

后处理

1. 1
   过滤the suspension was filtered over CELITE
2. 2
   workup.ADDITIONThe filtrate was diluted with diethyl ether
3. 3
   洗涤washed with saturated aqueous NaHCO3 and brine
4. 4
   干燥then dried over MgSO4
5. 5
   过滤filtered
6. 6
   浓缩concentrated

实验过程

1-(3a,6a-Dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone (453 mg, 2.48 mmol) was dissolved in THF (12 mL) and phenyltrimethylammonium tribromide (932 mg, 2.48 mmol) was added. After stirring for 1 h, the suspension was filtered over CELITE. The filtrate was diluted with diethyl ether, then washed with saturated aqueous NaHCO3 and brine then dried over MgSO4, filtered and concentrated to afford the title compound which was carried on without purification.

来源