反应 #1583861

反应方程式

dextromethorphan HBr

→

Dextromethorphan

溶剂

water

反应条件

后处理

1. 1
   workup.ADDITIONfollowed by the addition of 223.01 g AMBERLITE IRP-69 resin
2. 2
   workup.ADDITIONunder gentle mixing for 4 hours
3. 3
   其他was then decanted
4. 4
   洗涤rinsed with purified water twice
5. 5
   其他dried in an oven
6. 6
   温度maintained at 50° C. until the moisture content
7. 7
   过滤sieved through a 40 mesh screen

实验过程

Uncoated Dextromethorphan Resin Complex was prepared by first dissolving 119.28 g of dextromethorphan HBr in 1 L of purified water heated to 75-80° C., followed by the addition of 223.01 g AMBERLITE IRP-69 resin under gentle mixing for 4 hours. At the completion, the suspension was allowed to settle, and was then decanted and rinsed with purified water twice and dried in an oven maintained at 50° C. until the moisture content was around 5%. The dried resin complex was hand sieved through a 40 mesh screen.

来源