反应 #1573587

ord-78915987281748619bd18382a53ec2c7

反应方程式

N[C@H](C(=O)O)C1CCOCC1
(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid
COC(=O)N[C@H](C(=O)O)C(C)C
N-methoxycarbonyl-L-Valine
→
COC(=O)NC(C(=O)O)C1CCOCC1
2-(methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid

反应物

N[C@H](C(=O)O)C1CCOCC1
(S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid
COC(=O)N[C@H](C(=O)O)C(C)C
N-methoxycarbonyl-L-Valine

试剂

无

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

2-(methoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid was synthesized similar to N-methoxycarbonyl-L-Valine, using (S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid instead of L-Valine.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US09427428B2uspto-grants-2016_08