反应 #1563877

反应方程式

furan-2-yl(4,5,6,7-tetrachlorobenzo[d][1,3]dioxol-2-yl)methanone

phenylhydrazine

→

(2E)-2,2′-(1-(furan-2-yl)ethane-1,2-diylidene)bis(1-phenylhydrazine)

收率 87.0%

溶剂

ethanol

反应条件

后处理

1. 1
   温度was heated
2. 2
   温度under reflux for 30 minutes
3. 3
   其他During the course of the reflux, a yellow solid initially precipitated
4. 4
   workup.DISSOLUTIONdissolved upon further heating
5. 5
   其他The solvent was evaporated to dryness

实验过程

A mixture of furan-2-yl(4,5,6,7-tetrachlorobenzo[d][1,3]dioxol-2-yl)methanone (200 mg, 0.568 mmol) and phenylhydrazine (185 mg, 1.704 mmol) in ethanol (3 ml) was heated under reflux for 30 minutes. During the course of the reflux, a yellow solid initially precipitated, but then dissolved upon further heating. The solvent was evaporated to dryness, and the resulting crude material was subjected to flash column chromatography using 7% ethyl acetate/hexane as an eluent to yield (2E)-2,2′-(1-(furan-2-yl)ethane-1,2-diylidene)bis(1-phenylhydrazine) as a yellow solid (150 mg, 87%).

来源