反应 #155368

反应方程式

1b

3-[(3-Amino-4-methylamino-benzoyl)-phenyl-amino]-propionic acid methyl ester

N-(4-cyano-phenyl)-glycine

CDI

→

3-({3-[2-(4-Cyano-phenylamino)-acetylamino]-4-methylamino-benzoyl}-phenyl-amino)-propionic acid methyl ester

溶剂

THF

反应条件

后处理

1. 1
   其他After completion of the reaction the mixture
2. 2
   其他was evaporated to dryness
3. 3
   其他the crude product was used without further purification

实验过程

The product of 1b (23.2 mmol) and N-(4-cyano-phenyl)-glycine (23.2 mmol) were coupled with CDI (23.2 mmol) in dry THF at room temperature. After completion of the reaction the mixture was evaporated to dryness and the crude product was used without further purification.

来源