反应 #1509668

反应方程式

2,4-dichloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine

tyramine

→

title compound

4-(2-(2-chloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)ethyl)phenol

反应条件

后处理

1. 1
   其他The crude residue was purified by silica gel chromatography (25 to 75% ethyl acetate in hexane eluant)

实验过程

Following the procedure of Example 128b, 2,4-dichloro-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine (b) (0.278 g, 1.21 mmol) was reacted with tyramine. The crude residue was purified by silica gel chromatography (25 to 75% ethyl acetate in hexane eluant) to afford the title compound as a solid. MS m/z 331.1 (M+1).

来源