反应 #1509618
ord-6a5669c635e64ce09ba54932c7f11086
反应方程式
methylphenidate HCl
→
Methylphenidate
溶剂
反应条件
详细条件
See reaction.notes.procedure_details.
后处理
- 1其他The wet pellets are dried (Fluid Air Model#0050)
- 2过滤sieved (30 mesh<Acceptable<20 mesh)
实验过程
In a preferred manufacturing process, methylphenidate HCl and microcrystalline cellulose (Avicel PH-101) are blended in a Hobart Mixer. Purified water is added to the dry mixture and the wet granulation is extruded (MG-55 Multi granulator). The extrudate is then spheronized into pellets (Caleva Model#SPH1250). The wet pellets are dried (Fluid Air Model#0050) and sieved (30 mesh<Acceptable<20 mesh).