反应 #1483159

反应方程式

triethylamine

1-chlorooctane

→

triethyloctylammonium chloride

收率 11.0%

溶剂

acetonitrile

反应条件

后处理

1. 1
   其他manometer was purged with nitrogen
2. 2
   其他The autoclave was sealed
3. 3
   洗涤The crude product was subsequently washed with heptane and ethyl acetate

实验过程

A stainless-steel autoclave fitted with magnetic stirrer and manometer was purged with nitrogen and then charged with 36.13 g (0.357 mol) of triethylamine, 46.28 g (0.311 mol) of 1-chlorooctane and 81.40 g of acetonitrile. The autoclave was sealed and pressurized with 25 bar of nitrogen. The mixture in the autoclave was then heated to 80° C. and stirred for 48 hours. Thereafter, the superatmospheric pressure was released and the volatile constituents of the reaction mixture were drawn off under reduced pressure. The crude product was subsequently washed with heptane and ethyl acetate to obtain 8.30 g (0.033 mol) of triethyloctylammonium chloride (white hygroscopic salt). The yield was 11% based on 1-chlorooctane.

来源