反应 #1470456

反应方程式

10-methyloxacyclopentadec-9-en 2-one

→

10-methyloxacyclopentadecan-2-one

收率 62.0%

溶剂

ethanol

反应条件

后处理

1. 1
   过滤filtered over Celite
2. 2
   浓缩the solution was concentrated
3. 3
   其他chromatographed
4. 4
   workup.DISTILLATIONdistilled in a bulb-tube

实验过程

1.14 g of 10 percent palladium-on-carbon were added to 13.5 g (57 mol) of 10-methyloxacyclopentadec-9-en 2-one in 60 ml of ethanol and the mixture was subsequently hydrogenated under normal pressure for 6.5 hours. Then, it was suction filtered over Celite and the solution was concentrated, chromatographed and distilled in a bulb-tube. 8.4 g (62%) of 10-methyloxacyclopentadecan-2-one were obtained having the following characteristics:

来源