反应 #1466014

反应方程式

4-(3-oxo-3H-benzo[d]isothiazol-2-yl) benzenesulfonamide

tetrahydrofuran

2,3-dihydroxy-1-propanethiol

→

title compound

2-(2,3-Dihydroxypropyldisulfanyl)-N-(4-sulfamoylphenyl) benzamide

溶剂

methanol

反应条件

后处理

1. 1
   其他This compound was prepared
2. 2
   洗涤The product was washed with ether
3. 3
   其他dried in vacuo

实验过程

This compound was prepared according to the method of Example 132 using a suspension of 0.46 g (1.5 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl) benzenesulfonamide in a mixture of 15 mL of methanol, and 15 mL of tetrahydrofuran and 2,3-dihydroxy-1-propanethiol. The product was washed with ether and dried in vacuo to give 0.61 g of the title compound, mp >260° C.

来源